We'll see if the McCain campaign or the right-wing blogosphere tries to make hay out of Biden's comments.
Truth is, McCain is easy for opponents and enemies to manipulate, because he's rigid, as badly as King George "The Decider".
For instance, all you have to do to get him to act is taunt him. Ahmadi-Nejad would just have to call Israel a name or two and McCain would be dispatching the sixth fleet to ... wherever.